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Clinical Image
2 (
3
); 148-149
doi:
10.25259/WJWCH_2_2024

Bilateral complex microphthalmia with unilateral coloboma in a preterm neonate

Department of Neonatology, Seth GS Medical College and King Edward Memorial (KEM) Hospital, Mumbai, Maharashtra, India
Corresponding author: Sruthi Nair, Department of Neonatology, Seth GS Medical College and King Edward Memorial (KEM) Hospital, Mumbai, Maharashtra, India. sruthis.doc@gmail.com
Licence
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Bhadane A, Prashanth RR, Nair S, Haribalakrishna A. Bilateral complex microphthalmia with unilateral coloboma in a preterm neonate. Wadia J Women Child Health. 2023;2(3):148-9. doi: 10.25259/WJWCH_2_2024

A female neonate weighing 1300 g, born at 35 weeks of gestation with asymmetric intrauterine growth restriction had bilateral microphthalmia and microcornea [Figure 1] with no corneal haziness or cataracts. Fundus examination showed bilateral dysplastic retina. There were no other stigmata of intrauterine infection or any dysmorphism with normal systemic examination. B scan of the eyes showed an axial length of 14 mm in both eyes with iris coloboma in the right eye, confirming bilateral complex microphthalmia with unilateral coloboma [Figure 2]. TORCH titers, echocardiography, cranial ultrasound, skeletal survey, and automated auditory brainstem response (AABR) were normal. Parents denied genetic testing.

Figure 1:
Bilateral microphthalmia and microcornea.
Figure 2:
B scan of the eyes showed a right eye axial length measuring 14 mm with iris coloboma (white arrow) and a left eye axial length of 14 mm.

Microphthalmia and coloboma arise due to defects in the optic fissure closure and are diagnosed when the anteroposterior diameter of the globe is <20 mm.[1] Rehabilitation in these complex microphthalmia (when associated with retinal dysplasia) is for cosmetic purposes and includes endo-orbital volume replacement with expandable implants or orbital osteotomies.[2]

Ethical approval

Institutional Review Board approval is not required.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent.

Conflicts of interest

There are no conflicts of interest.

Use of artificial intelligence (AI)-assisted technology for manuscript preparation

The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.

Financial support and sponsorship

Nil.

References

  1. , . Anophthalmia and microphthalmia. Orphanet J Rare Dis. 2007;2:47.
    [CrossRef] [PubMed] [Google Scholar]
  2. , , , . Integrated reconstructive strategies for treating the anophthalmic orbit. J Craniomaxillofac Surg. 2004;32:279-90.
    [CrossRef] [PubMed] [Google Scholar]

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